Jin H, Li M, Jeong E, Castro-Martinez F, Zuker CS (2024). A body–brain circuit that regulates body inflammatory responses. Nature Accelerated Article Preview. [html] [pdf]

Zhang J, Villavicencio M, Zuker CS (2024). A neural substrate for short-term taste memories. Neuron 112: 277-287. [html] [pdf]

Li M, Tan H-E, Lu Z, Tsang K, Chung A, Zuker CS (2022). Gut–Brain Circuits for Fat Preference. Nature 610: 722-730. [html] [pdf]

Jin H, Fishman H, Ye M, Wang L, Zuker CS (2021). Top-Down Control of Sweet and Bitter Taste in the Mammalian Brain. Cell 184: 257-271. [html] [pdf]

Tan H-E, Sisti A, Jin H, Vignovich M, Villavicencio M, Tsang K, Goffer Y, Zuker CS (2020). The gut–brain axis mediates sugar preference. Nature 580: 511-516. [html] [pdf]

Zhang J, Jin H, Zhang W, Ding C, O'Keeffe S, Ye M, Zuker CS (2019). Sour Sensing from the Tongue to the Brain. Cell 179: 392-402. [html] [pdf]

Wang L, Gillis-Smith S, Peng Y, Zhang J, Chen X, Salzman CD, Ryba NJ, Zuker CS (2018). The coding of valence and identity in the mammalian taste system. Nature 558: 127-131. [html] [pdf]

Lee H, Macpherson LJ, Parada CA, Zuker CS, Ryba NJ (2017). Rewiring the taste system. Nature 548: 330-333. [html] [pdf]

Yarmolinsky DA, Peng Y, Pogorzala L, Rutlin M, Hoon MA, Zuker CS (2016). Coding and Plasticity in the Mammalian Thermosensory System. Neuron 92: 1079-1092. [html] [pdf]

Peng Y, Gillis-Smith S, Jin H, Tränkner D, Ryba NJ, Zuker CS (2015). Sweet and bitter taste in the brain of awake behaving animals. Nature 527: 512-515. [html] [pdf]

Zuker C (2015). Food for the brain. Cell 161: 9-11. [html] [pdf]

Oka Y, Ye M, Zuker C (2015). Thirst driving and suppressing signals encoded by distinct neural populations in the brain. Nature 520: 349-352. [html] [pdf]

Barretto R, Gillis-Smith S, Chandrashekar J, Yarmolinsky DA, Schnitzer M, Ryba NJ, Zuker C (2014). The neural representation of taste quality at the periphery. Nature 517: 373-376. [html] [pdf]

Tränkner D, Hahne N, Sugino K, Hoon MA, Zuker C (2014). Population of sensory neurons essential for asthmatic hyperreactivity of inflamed airways. PNAS 111 (31): 11515-11520. [html] [pdf]

Oka Y, Butnaru M, von Buchholtz L, Ryba NJ, Zuker CS (2013). High Salt Recruits Aversive Taste Pathways. Nature 494: 472-475. [html] [pdf]

Chen X, Gabitto M, Peng Y, Ryba NJ, Zuker CS (2011). A Gustotopic Map of Taste Qualities in the Mammalian Brain. Science 333: 1262-1266. [html] [pdf]

Ofstad TA, Zuker CS, Reiser MB (2011). Visual place learning in Drosophila melanogaster. Nature 474: 204-207. [html] [pdf]

Gallio M, Ofstad TA, Macpherson LJ, Wang JW, Zuker CS (2011). The coding of temperature in the Drosophila brain. Cell 144: 614-624. [html] [pdf]

Chandrashekar J, Kuhn C, Oka Y, Yarmolinsky DA, Hummler E, Ryba NJ, Zuker CS (2010). The cells and peripheral representation of sodium taste in mice. Nature 464: 297-301. [html] [pdf]

Chandrashekar J, Yarmolinsky DA, von Buchholtz L, Oka Y, Sly W, Ryba NJ, Zuker CS (2009). The taste of carbonation. Science 326: 443-445. [html] [pdf]

Yarmolinsky DA, Zuker CS, Ryba NJ (2009). Common sense about taste: from mammals to insects. Cell 139: 234-244. [html] [pdf]

Cook B, Hardy RW, McConnaughey WB, Zuker CS (2008). Preserving cell shape under environmental stress. Nature 452: 361-364. [html] [pdf]

Chandrashekar J, Hoon MA, Ryba NJ, Zuker CS (2006). The receptors and cells for mammalian taste. Nature 444: 288-294. [html] [pdf]

Zelhof AC, Hardy RW, Becker A, Zuker CS (2006). Transforming the architecture of compound eyes. Nature 443: 696-699. [html] [pdf]

Huang AL, Chen X, Hoon MA, Chandrashekar J, Guo W, Trankner D, Ryba NJ, Zuker CS (2006). The cells and logic for mammalian sour taste detection. Nature 442: 934-938. [html] [pdf]

Mueller KL, Hoon MA, Erlenbach I, Chandrashekar J, Zuker CS, Ryba NJ (2005). The receptors and coding logic for bitter taste. Nature 434: 225-229. [html] [pdf]

Avidor-Reiss T, Maer AM, Koundakjian E, Polyanovsky A, Keil T, Subramaniam, Zuker CS (2004). Decoding cilia function: defining specialized genes required for compartmentalized cilia biogenesis. Cell 117: 527-539. [html] [pdf]

Zhao GQ, Zhang Y, Hoon MA, Chandrashekar J, Erlenbach I, Ryba NJ, Zuker CS (2003). The receptors for mammalian sweet and umami taste. Cell 115: 255-266. [html] [pdf]

Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). Coding of sweet, bitter and umami tastes: Different receptor cells sharing similar signaling pathways. Cell 112: 293-301. [html] [pdf]

Nelson G, Chandrashekar J, Hoon MA, Feng L, Zhao G, Ryba NJ, Zuker CS (2002). An amino-acid taste receptor. Nature 416: 199-202. [html] [pdf]

Nelson G, Hoon MA, Chandrashekar J, Zhang Y, Ryba NJ, Zuker CS (2001). Mammalian sweet taste receptors. Cell 106: 381-390. [html] [pdf]

Scott K, Brady Jr. R, Cravchik A, Morozov P, Rzhetsky A, Zuker CS, Axel R (2001). A chemosensory gene family encoding candidate gustatory and olfactory receptors in Drosophila. Cell 104: 661-673. [html] [pdf]

Tsunoda S, Suzuki E, Zuker CS (2001). Independent anchoring and assembly mechanisms of INAD signaling complexes in Drosophila photoreceptors. J. Neurosci. 21: 150-158. [html] [pdf]

Kiselev A, Socolich M, Vinos J, Hardy RW, Zuker CS, Ranganathan R (2000). A molecular pathway for light-dependent photoreceptor apoptosis in Drosophila. Neuron 28: 139-152. [html] [pdf]

Chandrashekar J, Mueller KL, Hoon MA, Adler E, Feng L, Guo W, Zuker CS, Ryba NJ (2000). T2Rs function as bitter taste receptors. Cell 100: 703-711. [html] [pdf]

Adler E, Hoon MA, Mueller KL, Chandrashekar J, Ryba NJ, Zuker CS (2000). A novel family of mammalian taste receptors. Cell 100: 693-702. [html] [pdf]

Walker RG, Willingham AT, Zuker CS (2000). A Drosophila mechanosensory transduction channel. Science 287: 2229-2234. [html] [pdf]

Roger Tsien - Obituary 2016 [pdf]

Selected Publications Pre-2000

Zuker, C.S. and Ranganathan, R (1999). The Path to Specificity. Science 283: 650-651. [pdf]

Scott, K., and Zuker, C.S. (1998). Assembly of the Drosophila phototransduction cascade into a signaling complex shapes elementary responses. Nature 395: 805-808. [pdf]

Acharya, J.K., Labarca, P., Delgado, R., Jalink, K. and Zuker, C.S. (1998). Synaptic defects and compensatory regulation of inositol metabolism in inositol polyphosphate 1-phosphatase mutants. Neuron 20: 1219-1229. [pdf]

Scott, K., Sun, Y., Beckingham, K. and Zuker, C.S. (1997). Calmodulin regulation of Drosophila light-activated channels and receptor function mediates termination of the light response in vivo. Cell 91: 375-383. [pdf]

Tsunoda, S., Sierralta, J., Sun, Y., Bodner, R., Suzuki, E., Becker, A., Socolich, M. and Zuker, C.S. (1997). A multivalent PDZ-domain protein assembles signaling complexes in a G-protein-coupled signaling cascade. Nature 388: 243-249. [pdf]

Vinos, J., Jalink, K., Hardy, R.W., Britt, S.G. and Zuker, C.S. (1997). A G protein-coupled receptor phosphatase required for rhodopsin function. Science 277: 687-690. [pdf]

Acharya, J.K., Jalink, K., Hardy, R.W., Hartenstein, V. and Zuker, C.S. (1997). InsP3 receptor is essential for growth and differentiation but not for vision in Drosophila. Neuron 18: 881-887. [pdf]

Niemeyer, B.A., Suzuki, E., Scott, K., Jalink, K. and Zuker, C.S. (1996). The Drosophila light-activated conductance is composed of the two channels TRP and TRPL. Cell 85: 651-659. [pdf]

Scott, K., Becker, A., Sun, Y., Hardy, R. and Zuker, C. (1995). Gq alpha protein function in vivo: genetic dissection of its role in photoreceptor cell physiology. Neuron 15: 919-927. [pdf]

Wu, L., Niemeyer, B., Colley, N., Socolich, M. and Zuker, C.S. (1995). Regulation of PLC-mediated signalling in vivo by CDP-diacylglycerol synthase. Nature 373: 216-222. [pdf]

Rutherford, S.L. and Zuker, C.S. (1994). Protein folding and the regulation of signaling pathways. Cell 79: 1129-1132. [pdf]

Ranganathan, R., Bacskai, B.J., Tsien, R.Y. and Zuker, C.S. (1994). Cytosolic calcium transients: spatial localization and role in Drosophila photoreceptor cell function. Neuron 13: 837-848. [pdf]

Baker, E.B., Colley, N.J. and Zuker, C.S. (1994). The cyclophilin homolog NinaA functions as a chaperone, forming a stable complex in vivo with its protein target rhodopsin. EMBO 13: 4886-4895. [pdf]

Zuker, C.S. (1994). On the evolution of eyes: would you like it simple or compound? Science 265: 742-743. [pdf]

Kernan, M., Cowan, D. and Zuker, C. (1994). Genetic dissection of mechanosensory transduction: mechanoreception-defective mutations of Drosophila. Neuron 12: 1195-1206. [pdf]

Dolph, P.J., Man-Son-Hing, H., Yarfitz, S., Colley, N.J., Deer, J.R., Spencer, M., Hurley, J.B. and Zuker, C.S. (1994). An eye-specific G beta subunit essential for termination of the phototransduction cascade. Nature 370: 59-61. [pdf]

Dolph, P.J., Ranganathan, R., Colley, N.J., Hardy, R.W., Socolich, M. and Zuker, C.S. (1993). Arrestin function in inactivation of G protein-coupled receptor rhodopsin in vivo. Science 260: 1910-1916. [pdf]

Britt, S.G., Feiler, R., Kirschfeld, K. and Zuker, C.S. (1993). Spectral tuning of rhodopsin and metarhodopsin in vivo. Neuron 11: 29-39. [pdf]

Ondek, B., Hardy, R.W., Baker, E.K., Stamnes, M.A., Shieh, B.H. and Zuker, C.S. (1992). Genetic dissection of cyclophilin function. Saturation mutagenesis of the Drosophila cyclophilin homolog ninaA. J. Biol. Chem. 267: 16460-16466. [pdf]

Cassill, J. A., Whitney, M., Joazeiro, C.A., Becker, A. and Zuker, C.S. (1991). Isolation of Drosophila genes encoding G protein-coupled receptor kinases. Proc. Natl. Acad. Sci. (U.S.A.) 88: 11067-11070. [pdf]

Smith, D. P., Ranganathan, R., Hardy, R.W., Marx, J., Tsuchida, T. and Zuker, C.S. (1991). Photoreceptor deactivation and retinal degeneration mediated by a photoreceptor-specific protein kinase C. Science 254: 1478-1484. [pdf]

Ranganathan, R., Harris, G.L., Stevens, C.F., and Zuker, C.S. (1991). A Drosophila mutant defective in extracellular calcium-dependent photoreceptor deactivation and rapid desensitization. Nature 354: 230-232. [pdf]

Colley, N. J., Baker, E.K., Stamnes, M.A. and Zuker, C.S. (1991). The cyclophilin homolog ninaA is required in the secretory pathway. Cell 67: 255-263. [pdf]

Stamnes, M.A., Shieh, B.H., Chuman, L., Harris, G.L. and Zuker, C.S. (1991). The cyclophilin homolog ninaA is a tissue-specific integral membrane protein required for the proper synthesis of a subset of Drosophila rhodopsins. Cell 65: 219-227. [pdf]

Schaeffer, E., D. Smith, G. Mardon, W. Quinn and C. Zuker (1989). Isolation and characterization of two new Drosophila protein kinase C genes, including one specifically expressed in photoreceptor cells. Cell 57: 403-412. [pdf]

Shieh, B.-H., M. A. Stamnes, S. Seavello, G. Harris and C. Zuker (1989). The nina A gene required for visual transduction in Drosophila, encodes a homologue of the cyclosporin A binding protein. Nature 338: 67-70. [pdf]

Feiler, R., W. Harris, K. Kirschfeld, C. Wehrhahn and C. Zuker (1988). Targeted misexpression of a Drosophila opsin gene leads to altered visual function. Nature 333: 737-741. [pdf]